Chemotherapy-induced peripheral neuropathy (CIPN) is nerve damage caused by some cancer medicines, usually starting as tingling or numbness in the fingers and toes. It is common with platinum drugs (oxaliplatin, cisplatin), taxanes (paclitaxel, docetaxel), vinca alkaloids and bortezomib. It can improve after treatment ends, but for some people it lasts months or years.
Symptoms
- Tingling, numbness or burning in hands and feet
- Cold sensitivity (especially with oxaliplatin)
- Trouble with buttons, writing or balance
Burning, numb or tingling feet for months? Get the free guide and a doctor review of your scan.
During chemotherapy
Tell your oncology team early. They may adjust the dose or schedule. Never change cancer treatment on your own.
Treatment after chemotherapy
- Duloxetine is the one medicine the American Society of Clinical Oncology (ASCO) says may be offered for painful CIPN
- Exercise and balance training
- Foot and hand protection
- Physiotherapy and occupational therapy
Supportive regenerative care
Some cancer survivors with lasting neuropathy ask about PRP or stem cell approaches to ease symptoms. These are early research, not a cancer treatment, and should only be considered with your oncologist's agreement, usually after cancer treatment is complete.